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Publication : The mouse: genetics meets behaviour.

First Author  Bućan M Year  2002
Journal  Nat Rev Genet Volume  3
Issue  2 Pages  114-23
PubMed ID  11836505 Mgi Jnum  J:74734
Mgi Id  MGI:2159041 Doi  10.1038/nrg728
Citation  Bucan M, et al. (2002) The mouse: genetics meets behaviour. Nat Rev Genet 3(2):114-23
abstractText  Genetic studies in the mouse are important in the elucidation of molecular pathways that underlie behaviour. The advantages of the mouse for behavioural studies include an extensive array of genetic technologies and an elaborate behavioural repertoire that can be used to create models of human disease. This review discusses the relative advantages of forward and reverse genetic approaches to studying the genetic basis of behaviour in the mouse, and the complexities that behavioural studies need to address, such as phenotypic variability, genetic background effects and pleiotropy.
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