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Allele : Tg(Myh6-TNNI3*G203S)1Chs transgene insertion 1, Christopher Semsarian

Primary Identifier  MGI:3690009 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Myh6-TNNI3*G203S)1Chs
Is Recombinase  false Is Wild Type  false
molecularNote  This transgene consists of human TNNI3, with an amino acid substitution of a glycine by serine at codon 203 that causes familial hypertrophic cardiomyopathy in humans, under the control of the cardiac specific alpha-myosin heavy chain promoter. This line expresses the highest amount of mutant protein and represents relative proportions of mutant protein of 83%.
  • mutations:
  • Insertion
  • synonyms:
  • cTnI-G203S,
  • cTnI-G203S
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

12 Publication categories

Trail: Allele