| Primary Identifier | IPR005831 | Type | Conserved_site |
| Short Name | Aerolysin/haemolysin_CS |
| description | Aerolysin is a cytolytic toxin exported by the Gram-negative Aeromonasbacteria []. The mature toxin binds to eukaryotic cells and aggregates to formholes (approximately 3 nm in diameter) leading to the destruction of themembrane permeability barrier and osmotic lysis. Staphylococcus aureus also exports a cytotoxin, alpha-toxin, whose biological activity is similar to that of aerolysin. The sequences of both toxins are not similar except for a stretch of ten residues rather well conserved. |
