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Allele : Plbd2<em1(IMPC)J> phospholipase B domain containing 2; endonuclease-mediated mutation 1, Jackson

Primary Identifier  MGI:6356392 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Plbd2
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NJ
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences ACATGCATCAACCCCACTGA and AGCAGTTGCCTGCCACACGA, which resulted in a 324 bp deletion beginning at Chromosome 5 position 120,498,915 bp and ending after 120,499,238 bp (GRCm38/mm10). This mutation deletes ENSMUSE00001254826 (exon 2) and 230 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 102 and early truncation 6 amino acids later.
  • mutations:
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele