First Author | Nomura T | Year | 1993 |
Journal | Biochem Biophys Res Commun | Volume | 191 |
Issue | 2 | Pages | 523-7 |
PubMed ID | 8461009 | Mgi Jnum | J:4167 |
Mgi Id | MGI:52666 | Doi | 10.1006/bbrc.1993.1249 |
Citation | Nomura T, et al. (1993) Cloning and sequencing of cDNA encoding mouse GTP cyclohydrolase I. Biochem Biophys Res Commun 191(2):523-7 |
abstractText | A full-length cDNA clone for GTP cyclohydrolase I (EC 3.5.4.16) was isolated from a mouse brain cDNA library by plaque hybridization. The nucleotide sequence determination revealed that the length of the cDNA insert was 994 base pairs. The coding region encoded a protein of 241 amino acid residues with a calculated molecular mass of 27,014 daltons. The deduced amino acid sequence of mouse GTP cyclohydrolase I was found to be highly homologous to rat (96%) and human type 1 (89%) enzymes. |