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Publication : Sequences of two porcine glutamic acid decarboxylases (65- and 67-kDa GAD).

First Author  Suzuki R Year  1995
Journal  Gene Volume  152
Issue  2 Pages  257-60
PubMed ID  7835711 Mgi Jnum  J:23226
Mgi Id  MGI:70995 Doi  10.1016/0378-1119(94)00713-3
Citation  Suzuki R, et al. (1995) Sequences of two porcine glutamic acid decarboxylases (65- and 67-kDa GAD). Gene 152(2):257-60
abstractText  The cDNAs encoding the porcine 65- and 67-kDa glutamic acid decarboxylases (GAD65 and GAD67, respectively) were cloned by the PCR method. The 2246-nucleotide (nt) GAD65 cDNA contained an open reading frame (ORF) coding for a protein of 585 amino acids (aa), and the 3262-nt GAD67 cDNA contained an ORF coding for a protein of 594 aa. A remarkable conservation was shown when the deduced aa sequences of porcine GAD65 and GAD67 were compared with those of other mammalian species (human, cat and rat). Porcine GAD65 is 96% identical to human and rat GAD65, and porcine GAD67 is more than 95% identical to human, cat and rat GAD67 at the aa level.
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