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Allele : Nefl<tm1Jpj> neurofilament, light polypeptide; targeted mutation 1, Jean-Pierre Julien

Primary Identifier  MGI:2180095 Allele Type  Targeted
Attribute String  Null/knockout Gene  Nefl
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  0.7 kb of the gene including exon 1 was replaced with a neomycin resistance cassette by homologous recombination. Northern and Western blots of brain and nervous tissue from homozygous mutant animals did not detect gene expression, nor were any truncated mRNA species or protein fragments detected.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • L-,
  • NF-L-,
  • NFL-,
  • NF-L-,
  • NFL-,
  • L-
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

38 Publication categories

Trail: Allele