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Protein Coding Gene : Taf7 TATA-box binding protein associated factor 7

Primary Identifier  MGI:1346348 Organism  mouse, laboratory
Chromosome  18 NCBI Gene Number  24074
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables histone acetyltransferase binding activity. Acts upstream of or within intracellular estrogen receptor signaling pathway; regulation of transcription by RNA polymerase II; and transcription by RNA polymerase II. Located in cytoplasm and male germ cell nucleus. Part of transcription factor TFIID complex. Is expressed in blastocyst; brain; genitourinary system; and tail. Orthologous to human TAF7 (TATA-box binding protein associated factor 7).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit embryonic lethality between E3.5 and E5.5. Mice homozygous for a conditional allele activated in thymocytes exhibit impaired T cell differentiation. [provided by MGI curators]
  • synonyms:
  • expressed sequence AI607308,
  • BB007175,
  • Taf7,
  • TATA box binding protein (TBP) associated factor, RNA polymerase II, F, 55 kDa,
  • TATA-box binding protein associated factor 7,
  • 55kDa,
  • TAFII55,
  • expressed sequence BB007175,
  • MGI:2147246,
  • AI607308,
  • Taf2f,
  • MGI:2147382

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

5 Involved In Mutations

0 Strain

0 Transcripts

1 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

11 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For