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Allele : Del(5Cyp3a57-Cyp3a59)2Nki deletion, Chr 5, The Netherlands Cancer Institute 2

Primary Identifier  MGI:3775604 Allele Type  Targeted
Gene  Del(5Cyp3a57-Cyp3a59)2Nki Transmission  Germline
Strain of Origin  129P2/OlaHsd Is Recombinase  false
Is Wild Type  false
molecularNote  The intronic sequence between exon 2 and 3 of Cyp3a57 was replaced with a floxed neo cassette and 2.2 kb downstream of exon 13 a thymidine kinase and a floxed hygromycin cassette were inserted into the genomic sequence of Cyp3a59. Transfection of ES cells with a cre recombinase resulted in the deletion of Cyp3a57, Cyp3a16, Cyp3a41, Cyp3a44, Cyp3a11, Cyp3a25 and Cyp3a59.
  • mutations:
  • Intragenic deletion,
  • Intergenic deletion
  • synonyms:
  • Del2Nki,
  • Del(5Cyp3a57-Cyp3a59)1Ahs,
  • Del1Ahs,
  • Cyp3a<tm1.1Ahs>,
  • Del1Ahs,
  • Del2Nki,
  • Cyp3a<tm1.1Ahs>,
  • Del(5Cyp3a57-Cyp3a59)1Ahs
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1 Feature

Trail: Allele

Genome

0 Expresses

17 Mutation Involves

Trail: Allele

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

5 Carried By

Trail: Allele

0 Driven By

6 Publication categories

Trail: Allele