| Primary Identifier | MGI:3806010 | Allele Type | Chemically induced (ENU) |
| Gene | Atp7a | Inheritance Mode | Semidominant |
| Strain of Origin | C57BL/6J | Is Recombinase | false |
| Is Wild Type | false | Project Collection | Beutler Mutagenetix |
| molecularNote | The Tigrou mutation, discovered in a G1 daughter of an ENU-mutagenized male mouse, corresponds to a G-to-T transversion at nucleotide position 1485 of the gene, in the fifth of 23 total exons. It results in replacement of the glutamic acid codon at position 469 by a stop codon (E469Ter), which would truncate the protein before the fifth metal binding domain. It is unknown whether this truncated protein is expressed in mutant mice. |
