Primary Identifier | MGI:7564507 | Allele Type | Endonuclease-mediated |
Attribute String | Not Specified | Gene | Bcl11b |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | CRISPR-targeting introduced the mutation responsible for the amino acid substitution of arginine with serine at position three (R3S). This mutation replicates on identified in patients with craniosynostosis. |