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Allele : Bcl11b<em1Srft> B cell leukemia/lymphoma 11B; endonuclease-mediated mutation 1, Stephen RF Twigg

Primary Identifier  MGI:7564507 Allele Type  Endonuclease-mediated
Attribute String  Not Specified Gene  Bcl11b
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  CRISPR-targeting introduced the mutation responsible for the amino acid substitution of arginine with serine at position three (R3S). This mutation replicates on identified in patients with craniosynostosis.
  • mutations:
  • Single point mutation
  • synonyms:
  • BCL11B p.R3S,
  • BCL11B p.R3S
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele