| Primary Identifier | MGI:1352757 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 29875 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Enables small GTPase binding activity. Involved in cellular response to epidermal growth factor stimulus; cellular response to platelet-derived growth factor stimulus; and transmembrane receptor protein tyrosine kinase signaling pathway. Acts upstream of or within fibroblast migration; negative regulation of dephosphorylation; and regulation of cytokine production. Located in several cellular components, including basolateral plasma membrane; focal adhesion; and lateral plasma membrane. Part of ribonucleoprotein complex. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; genitourinary system; and hemolymphoid system gland. Orthologous to human IQGAP1 (IQ motif containing GTPase activating protein 1). PHENOTYPE: Homozygotes for a targeted null allele exhibit a late-onset gastric hyperplasia. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
