| Primary Identifier | MGI:1098824 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 18286 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable small GTPase binding activity. Predicted to be involved in several processes, including centriole-centriole cohesion; cilium organization; and regulation of cilium assembly. Predicted to act upstream of or within cell differentiation and spermatogenesis. Located in centriole; centrosome; and sperm flagellum. Part of ciliary transition fiber. Is expressed in several structures, including brain; early conceptus; inner ear; liver; and reproductive system. Orthologous to human ODF2 (outer dense fiber of sperm tails 2). PHENOTYPE: Mice homozygous for a gene trapped allele exhibit embryonic lethality before implantation and transmission ratio distortion while all heterozygous males display normal development and fertility. Males heterozygous for other alleles are either infertile orshow reduced fertility. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
