Primary Identifier | MGI:1915196 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 67946 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Enables myosin light chain binding activity. Involved in motile cilium assembly and spermatogenesis. Located in sperm connecting piece. Is expressed in several structures, including adipose tissue; central nervous system; genitourinary system; gut; and liver and biliary system. Orthologous to human SPATA6 (spermatogenesis associated 6). PHENOTYPE: Mice homozygous for a null allele exhibit abnormal formation of the sperm connecting piece during late spermiogenesis, leading to acephalic spermatozoa and male infertility. [provided by MGI curators] |