|  Help  |  About  |  Contact Us

Protein Domain : Shroom3

Primary Identifier  IPR030494 Type  Family
Short Name  Shrm3
description  Protein Shroom3 (Shrm3) belongs to the Shroom family, whose members are linked to the actin cytoskeleton []. Shrm3 is an actin binding protein that directs Rho kinase- and RhoA-dependent apical constriction in the lens placode and partially facilitates invagination [, , , ]. It is recruited to adherens junctions by cadherin-binding ZA (zonula adherens) protein p120-catenin during lens pit morphogenesis []. It is necessary for neural tube closure in vertebrate development [, ].

0 Child Features

1 Parent Features

9 Protein Domain Regions