Primary Identifier | MGI:3693318 | Allele Type | Targeted |
Gene | Rims1 | Transmission | Germline |
Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Exon 6 was replaced with one in which nucleotide substitutions result in an amino acid substitution of alanine for serine at position 413 (S413A). A loxP site was inserted upstream of the modified exon 6 and an frt-flanked, double neo cassette with a 5' loxP site was inserted downstream of exon 6 and removed by germ line, flp mediated recombination. |