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Allele : Tg(Lrrk2)6Yue transgene insertion 6, Zhenyu Yue
Primary Identifier  MGI:4437427 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Lrrk2)6Yue
Strain of Origin  (C57BL/6 x C3H)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  Bacterial artificial chromosome (BAC) library (CHORI) was used to obtain a 240 kb BAC (#RP23-312I9) containing the entire mouse Lrrk2 (leucine-rich repeat kinase 2) gene. This BAC contains a FLAG-tag downstream from the start codon. Founder line 6 was established with expression in cerebral cortex, striatum, substantia nigra, internal capsule, and hippocampus at an approximately 6-8 fold greater level than endogenous mouse Lrrk2.
  • mutations:
  • Insertion
  • synonyms:
  • LRRK2-WT<OE>,
  • FLAG-LRRK2-WT,
  • FLAG-LRRK2-WT,
  • LRRK2-WT<OE>
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

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0 Driven By

12 Publication categories

Trail: Allele




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