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Protein Coding Gene : Oaz3 ornithine decarboxylase antizyme 3

Primary Identifier  MGI:1858170 Organism  mouse, laboratory
Chromosome  3 NCBI Gene Number  53814
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables ornithine decarboxylase inhibitor activity. Involved in negative regulation of polyamine transmembrane transport; positive regulation of intracellular protein transport; and positive regulation of protein catabolic process. Located in cytoplasm and nucleus. Orthologous to human OAZ3 (ornithine decarboxylase antizyme 3).
PHENOTYPE: Homozygotes for a targeted null mutation exhibit male infertility due to detachment of sperm tail and head during sperm maturation. [provided by MGI curators]
  • synonyms:
  • Oaz-t,
  • AZ-3,
  • ornithine decarboxylase antizyme 3,
  • AZ3,
  • Oaz3,
  • ornithine decarboxylase antizyme in testis,
  • antizyme 3

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

4 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For