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Publication : Genetic analysis of autoimmune type 1 diabetes mellitus in mice.

First Author  Todd JA Year  1991
Journal  Nature Volume  351
Issue  6327 Pages  542-7
PubMed ID  1675432 Mgi Jnum  J:3351
Mgi Id  MGI:51864 Doi  10.1038/351542a0
Citation  Todd JA, et al. (1991) Genetic analysis of autoimmune type 1 diabetes mellitus in mice [see comments]. Nature 351(6327):542-7
abstractText  Two genes, Idd-3 and Idd-4, that influence the onset of autoimmune type 1 diabetes in the nonobese diabetic mouse have been located on chromosomes 3 and 11, outside the chromosome 17 major histocompatibility complex. A genetic map of the mouse genome, analysed using the polymerase chain reaction, has been assembled specifically for the study. On the basis of comparative maps of the mouse and human genomes, the homologue of Idd-3 may reside on human chromosomes 1 or 4 and Idd-4 on chromosome 17.
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