| Primary Identifier | MGI:2663253 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 233549 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Enables 2-acylglycerol O-acyltransferase activity and acetyltransferase activity. Involved in triglyceride biosynthetic process. Acts upstream of or within diacylglycerol biosynthetic process and intestinal absorption. Predicted to be located in perinuclear endoplasmic reticulum membrane. Predicted to be active in endoplasmic reticulum membrane. Is expressed in several structures, including alimentary system; embryo endoderm; liver; metanephros; and yolk sac. Orthologous to human MOGAT2 (monoacylglycerol O-acyltransferase 2). PHENOTYPE: Mice homozygous for a null allele exhibit resistance to diet induced obesity, hyperinsulinemia, hyperlipidemia, and steatosis with decreased lipid absorption and increased oxygen consumption when fed a high fat diet. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
