First Author | Lukacs NW | Year | 1996 |
Journal | Pathobiology | Volume | 64 |
Issue | 6 | Pages | 308-13 |
PubMed ID | 9159024 | Mgi Jnum | J:40311 |
Mgi Id | MGI:87652 | Doi | 10.1159/000164065 |
Citation | Lukacs NW, et al. (1996) Airway hyperreactivity is associated with specific leukocyte subset infiltration in a mouse model of allergic airway inflammation. Pathobiology 64(6):308-13 |
abstractText | Airway hyperreactivity is defined as an increased bronchoconstrictor response to physical, pharmacological, or other stimuli. Patients with asthma develop airway hyperreactivity as well as peribronchial inflammation. We employed an established schistosome soluble egg antigen (SEA)-induced murine model of allergic inflammation to examine the temporal relationship between airway hyperreactivity and subset infiltration. Dose response curves of intravenous methacholine were used in mice to characterize airway |