Primary Identifier | MGI:3056648 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Kcnq1 |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A C to T transition resulting in an amino acid change of T311I was introduced in exon 7 via homologous recombination. Northern analysis showed that RNA is expressed at wild-type levels. Sequencing of amplified cDNA confirmed presence of the mutation. |