Primary Identifier | MGI:2652126 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Txk |
Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exon 6 was disrupted by the insertion of neo and multiple stop codons. Neither full length nor truncated protein products were detected by Western blot analyses of homozygous mutant lymphoid cell extracts. An splentocyte assay indicated an absence of endogenous kinase activity in homozygous mutant mice. |