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Allele : Txk<tm1Pls> TXK tyrosine kinase; targeted mutation 1, Pamela L Schwartzberg

Primary Identifier  MGI:2652126 Allele Type  Targeted
Attribute String  Null/knockout Gene  Txk
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 6 was disrupted by the insertion of neo and multiple stop codons. Neither full length nor truncated protein products were detected by Western blot analyses of homozygous mutant lymphoid cell extracts. An splentocyte assay indicated an absence of endogenous kinase activity in homozygous mutant mice.
  • mutations:
  • Insertion
  • synonyms:
  • rlk<->,
  • rlk<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

19 Publication categories

Trail: Allele