Primary Identifier | MGI:5751483 | Allele Type | Chemically induced (ENU) |
Attribute String | Hypomorph | Gene | Vps25 |
Inheritance Mode | Recessive | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
molecularNote | ENU mutagenesis induced a G to A transition in intron 3 that results in an in-frame 27 nucleotide insertion encoding 9 additional neutral amino acids. Western blot anlaysis confirmed reduced protein expression in E10.5 embryos. |