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Protein Coding Gene : Mchr1 melanin-concentrating hormone receptor 1

Primary Identifier  MGI:2180756 Organism  mouse, laboratory
Chromosome  15 NCBI Gene Number  207911
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables signaling receptor binding activity. Predicted to be involved in several processes, including neuropeptide signaling pathway; positive regulation of calcium ion transport; and positive regulation of cytosolic calcium ion concentration. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Located in ciliary membrane; neuron projection; and non-motile cilium. Is expressed in brain and lung. Human ortholog(s) of this gene implicated in morbid obesity. Orthologous to human MCHR1 (melanin concentrating hormone receptor 1).
PHENOTYPE: Homozygous mice for some alleles may display osteoporosis, resistance to diet-induced obesity, abnormal pyramidal neuron physiology, hyperactivity, polyphagia, increased heart rate and body temperature, sleep behavior, and impaired conditioned learning. [provided by MGI curators]
  • synonyms:
  • Mchr1,
  • melanin-concentrating hormone receptor 1,
  • G protein coupled receptor 24,
  • MGI:2146183,
  • Gpr24-9,
  • MCH-1R,
  • Mch1r,
  • expressed sequence AW049955,
  • AW049955,
  • Gpr24

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

3 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

12 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

3 Driver For