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Protein Coding Gene : Hapln2 hyaluronan and proteoglycan link protein 2

Primary Identifier  MGI:2137300 Organism  mouse, laboratory
Chromosome  3 NCBI Gene Number  73940
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable hyaluronic acid binding activity. Acts upstream of or within establishment of blood-nerve barrier and extracellular matrix assembly. Located in extracellular matrix and node of Ranvier. Is expressed in brain. Orthologous to human HAPLN2 (hyaluronan and proteoglycan link protein 2).
PHENOTYPE: Homozygous null mice display reduced nerve conduction velocity and abnormalities in the neuronal extracellular matrix. [provided by MGI curators]
  • synonyms:
  • MGI:1921190,
  • 4930401E20Rik,
  • Bral1,
  • RIKEN cDNA 4930401E20 gene,
  • Hapln2,
  • brain link protein 1,
  • hyaluronan and proteoglycan link protein 2

Features --> Cross References

Genome

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0 Canonical

0 CDSs

0 Exons

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2 Involved In Mutations

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0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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