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Publication : What a difference a phosphate makes: life or death decided by a single amino acid in MDM2.

First Author  Li YC Year  2012
Journal  Cancer Cell Volume  21
Issue  5 Pages  595-6
PubMed ID  22624708 Mgi Jnum  J:189303
Mgi Id  MGI:5445030 Doi  10.1016/j.ccr.2012.04.033
Citation  Li YC, et al. (2012) What a difference a phosphate makes: life or death decided by a single amino acid in MDM2. Cancer Cell 21(5):595-6
abstractText  In this issue of Cancer Cell, Gannon and colleagues create genetically engineered mice to test the role phosphorylation plays in the modification of one serine long thought to play a critical role in controlling the activity of MDM2, one of p53's main negative regulators.
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