| Primary Identifier | MGI:105305 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 20514 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Enables L-aspartate transmembrane transporter activity and neutral L-amino acid transmembrane transporter activity. Involved in L-aspartate import across plasma membrane and transport across blood-brain barrier. Acts upstream of or within amino acid transmembrane transport and neutral amino acid transport. Located in basal plasma membrane. Is active in plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; liver; and respiratory system. Orthologous to human SLC1A5 (solute carrier family 1 member 5). PHENOTYPE: Mice homozygous for a knock-out allele exhibit reduced B cells, CD4+ memory T cells in older mice, Th1 and Th17 T cells, susceptibility to EAE and T cell uptake of glutamine and leucine. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
