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Protein Coding Gene : Islr immunoglobulin superfamily containing leucine-rich repeat
Primary Identifier  MGI:1349645 Organism  mouse, laboratory
Chromosome  9 NCBI Gene Number  26968
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Located in extracellular space. Is expressed in several structures, including embryo mesenchyme; genitourinary system; gut gland; meninges; and retina layer. Orthologous to human ISLR (immunoglobulin superfamily containing leucine rich repeat).
PHENOTYPE: The gene product suppresses differentiation of bone marrow stromal and skeletal stem cells into skeletal lineages. Homozygous knockout leads to growth retardation and longer long bones. [provided by MGI curators]
  • synonyms:
  • expressed sequence AW553146,
  • Islr,
  • AW553146,
  • immunoglobulin superfamily containing leucine-rich repeat,
  • MGI:2143325
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Features --> Cross References

Genome

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0 Exons

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

4 Pathways

Trail: ProteinCodingGene

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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3 Driver For

Trail: ProteinCodingGene




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