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Protein Coding Gene : Trh thyrotropin releasing hormone

Primary Identifier  MGI:98823 Organism  mouse, laboratory
Chromosome  6 NCBI Gene Number  22044
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable thyrotropin-releasing hormone activity. Acts upstream of or within adult walking behavior. Predicted to be located in extracellular region. Predicted to be active in secretory granule. Is expressed in several structures, including embryo endoderm; gut; neural ectoderm; renal vasculature; and trigeminal ganglion. Orthologous to human TRH (thyrotropin releasing hormone).
PHENOTYPE: Homozygotes for targeted null mutations exhibit high postnatal mortality, impaired thermoregulation, and loss of white fat. Survivors show ketosis, microvesicular fat accumulation, elevated serum lipids, and behavioral abnormalities. [provided by MGI curators]
  • synonyms:
  • thyrotropin releasing hormone,
  • Trh,
  • AL022609,
  • AI324969,
  • MGI:2141394,
  • MGI:2141525,
  • expressed sequence AL022609,
  • MGD-MRK-15226,
  • expressed sequence AI324969

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

7 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

2 Driver For