First Author | Jacob CO | Year | 1993 |
Journal | Mamm Genome | Volume | 4 |
Issue | 8 | Pages | 435-9 |
PubMed ID | 8104057 | Mgi Jnum | J:13564 |
Mgi Id | MGI:61750 | Doi | 10.1007/BF00296817 |
Citation | Jacob CO, et al. (1993) Mapping of the interleukin 5 receptor gene to human chromosome 3 p25-p26 and to mouse chromosome 6 close to the Raf-1 locus with polymorphic tandem repeat sequences. Mamm Genome 4(8):435-9 |
abstractText | Simple-sequence tandem repeat sequences in the 3' UTR of interleukin 5 (IL5)-receptor gene of human and mouse are polymorphic in their length among humans and different strains of mice. In 20 different human Epstein-Barr virus (EBV)-transformed cell lines, six alleles of IL5R could be distinguished. In the mouse, three different alleles are found. With the human-specific IL5R tandem repeat marker in human-rodent somatic cell hybrids, the IL5R gene was mapped to human Chromosome (Chr) 3 p25-p26. With the mouse-specific IL5R tandem repeat sequence in recombinant inbred strains of mice, the Il5r gene was mapped to the distal part of mouse Chr 6 close to the Raf-1 locus. |