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Allele : Tmem95<em1Beal> transmembrane protein 95; endonuclease-mediated mutation 1, Pablo Bermejo-Alvarez

Primary Identifier  MGI:6460450 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Tmem95
Strain of Origin  (CBA x C57BL/6)F2 Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/cas9 mediated recombination created a 4bp substitution (ACTT to GAAG) followed by a 10 bp deletion (CGGCTTCGTC) in exon 1 predicted to result in a truncated transcript. Immunohistochemical analysis confirmed the absence of protein expression in sperm from homozygous mice.
  • mutations:
  • Nucleotide substitutions,
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele