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Protein Coding Gene : Dnajc3 DnaJ heat shock protein family (Hsp40) member C3
Primary Identifier  MGI:107373 Organism  mouse, laboratory
Chromosome  14 NCBI Gene Number  100037258
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.3.0)

Enables several functions, including misfolded protein binding activity; protein kinase inhibitor activity; and protein-folding chaperone binding activity. Involved in cellular response to cold; proteolysis involved in protein catabolic process; and regulation of translational initiation. Located in cytosol and endoplasmic reticulum lumen. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Orthologous to human DNAJC3 (DnaJ heat shock protein family (Hsp40) member C3).
PHENOTYPE: Homozygous null mice are smaller in size, have a lower percentage of body fat and develop a gradual onset of glucosuria and hyperglycemia associated with increasing apoptosis of pancreatic islet cells. [provided by MGI curators]
  • synonyms:
  • MGD-MRK-35840,
  • p58IPK,
  • DnaJ (Hsp40) homolog, subfamily C, member 3A,
  • AA408985,
  • expressed sequence AA408985,
  • Dnajc3b,
  • Dnajc3a,
  • AU067833,
  • mp58,
  • DnaJ (Hsp40) homolog, subfamily C, member 3B,
  • DnaJ (Hsp40) homolog, subfamily C, member 3,
  • MGI:2145768,
  • Prkri,
  • protein kinase, interferon inducible double stranded RNA dependent inhibitor,
  • MGI:2145552,
  • expressed sequence AU067833,
  • protein kinase, interferon indducible double stranded RNA dependent inhibitor,
  • Dnajc3,
  • DnaJ heat shock protein family (Hsp40) member C3,
  • MGI:3696572
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2 Involved In Mutations

Trail: ProteinCodingGene

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Trail: ProteinCodingGene

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