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Protein Coding Gene : Ucn urocortin

Primary Identifier  MGI:1276123 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  22226
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable corticotropin-releasing hormone receptor 1 binding activity; corticotropin-releasing hormone receptor 2 binding activity; and histone deacetylase inhibitor activity. Involved in positive regulation of transcription by RNA polymerase II; response to auditory stimulus; and startle response. Predicted to be located in axon; dendrite; and perikaryon. Is expressed in brain. Orthologous to human UCN (urocortin).
PHENOTYPE: Homozygous null mutant mice exhibit impaired hearing and reduced acoustic startle response associated with a reduction in outer hair cell length. In addition, some mutant mice exhibit elevated anxiety-like behaviors. [provided by MGI curators]
  • synonyms:
  • Ucn1,
  • Ucn,
  • urocortin

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

5 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

4 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For