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Allele : Fn1<tm1Hyn> fibronectin 1; targeted mutation 1, Richard Hynes
Primary Identifier  MGI:1857170 Allele Type  Targeted
Attribute String  Null/knockout Gene  Fn1
Transmission  Germline Strain of Origin  129S2/SvPas
Is Recombinase  false Is Wild Type  false
molecularNote  A PGK-neomycin resistance cassette replaced 0.8 kb of the gene including the translation initiation site and part of the signaling sequence. Plasma concentrations of fibronectin in heterozygotes were one-half those of wild-type littermates. The encoded protein was not detectable in immunoprecipitations from cultures of homozygous mutant E7.5 embryos.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Fn<->,
  • FN.null,
  • FN.null,
  • Fn<->,
  • FN<null>,
  • FN<null>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

4 Carried By

Trail: Allele

0 Driven By

16 Publication categories

Trail: Allele




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