| First Author | Diman NY | Year | 2004 |
| Journal | Brain Res Dev Brain Res | Volume | 150 |
| Issue | 2 | Pages | 211-3 |
| PubMed ID | 15158084 | Mgi Jnum | J:92198 |
| Mgi Id | MGI:3051939 | Doi | 10.1016/j.devbrainres.2004.03.013 |
| Citation | Diman NY, et al. (2004) The proximal 2-kb of the Hoxa3 promoter directs gene expression in distinct branchial compartments and cranial ganglia. Brain Res Dev Brain Res 150(2):211-3 |
| abstractText | Developing structures such as hindbrain, neural crest cells or spinal cord express Hoxa3. Here, we have investigated the regulatory role of a 2-kb fragment spanning the proximal promoter of Hoxa3 by a reporter-based approach in mice. We show that this fragment promotes reporter activity in ganglionic and branchial compartments known to express Hoxa3 but for which no cis-regulatory elements have been identified so far. We also show that the 2-kb promoter fragment is active in rhombomere 4 and in the ganglion of the cranial nerve complex VII/VIII that are devoid of Hoxa3 expression. |
