| Primary Identifier | MGI:3029632 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 327987 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable nuclear thyroid hormone receptor binding activity and transcription coactivator activity. Involved in cholesterol homeostasis and triglyceride homeostasis. Part of mediator complex. Is expressed in several structures, including early embryo; gut; hemolymphoid system gland; reproductive system; and submandibular gland primordium. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder. Orthologous to human MED13 (mediator complex subunit 13). PHENOTYPE: Mice homozygous for a conditional allele exhibited in the heart exhibit increased susceptibility to obesity and worsened glucose intolerance when fed a high fat diet. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
