Primary Identifier | MGI:1917360 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 70110 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable identical protein binding activity. Involved in positive regulation of inflammatory response; positive regulation of innate immune response; and positive regulation of non-canonical NF-kappaB signal transduction. Located in extracellular space. Is expressed in bladder. Orthologous to human IFI35 (interferon induced protein 35). PHENOTYPE: Mice homozygous for a different null allele exhibit reduced susceptibility to LPS treatment. [provided by MGI curators] |