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Protein Coding Gene : Tarbp2 TARBP2, RISC loading complex RNA binding subunit

Primary Identifier  MGI:103027 Organism  mouse, laboratory
Chromosome  15 NCBI Gene Number  21357
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable several functions, including RNA binding activity; protein homodimerization activity; and protein sequestering activity. Predicted to contribute to pre-miRNA binding activity. Acts upstream of or within several processes, including positive regulation of muscle cell differentiation; regulation of gene expression; and spermatid development. Part of RISC complex. Is expressed in brain and early embryo. Orthologous to human TARBP2 (TARBP2 subunit of RISC loading complex).
PHENOTYPE: Homozygous inactivation of this gene results in lethality at weaning, decreased body weight, and male infertility associated with oligozoospermia and failure of spermiation. [provided by MGI curators]
  • synonyms:
  • TARBP2, RISC loading complex RNA binding subunit,
  • protamine RNA binding protein,
  • MGI:108201,
  • TRBP,
  • Prbp,
  • Tarbp2,
  • MGD-MRK-23864,
  • MGD-MRK-37240

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

3 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

9 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For