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Publication : Rig-1 a new member of Robo family genes exhibits distinct pattern of expression during mouse development.

First Author  Camurri L Year  2004
Journal  Gene Expr Patterns Volume  4
Issue  1 Pages  99-103
PubMed ID  14678835 Mgi Jnum  J:87380
Mgi Id  MGI:2686781 Doi  10.1016/s1567-133x(03)00142-x
Citation  Camurri L, et al. (2004) Rig-1 a new member of Robo family genes exhibits distinct pattern of expression during mouse development. Gene Expr Patterns 4(1):99-103
abstractText  The Robo genes encode a family of proteins that are the receptors for the midline repellent Slits and play a role in axon guidance. In addition to Robo1 and Robo2, Rig-1 has been recently identified in mouse as a novel member of the Robo family of proteins. As a first step in elucidating the role of Rig-1 during vertebrate development, we characterised the expression of Rig-1 by in situ hybridisation together with Robo1 and Robo2 in the spinal cord and other tissues of the mouse embryo. Our results show that Rig-1 has a dynamic pattern of expression in the developing CNS. In the spinal cord Rig-1 shows overlapping but distinct pattern of expression with Robo1 and Robo2.
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