Primary Identifier | IPR028341 | Type | Family |
Short Name | Complement_B |
description | This group represents a complement factor B. Factor B is part of the alternate pathway of the complement system. It is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation [, ]. |