| First Author | Beutler B | Year | 1986 |
| Journal | Nature | Volume | 320 |
| Issue | 6063 | Pages | 584-8 |
| PubMed ID | 3010124 | Mgi Jnum | J:30781 |
| Mgi Id | MGI:78596 | Doi | 10.1038/320584a0 |
| Citation | Beutler B, et al. (1986) Cachectin and tumour necrosis factor as two sides of the same biological coin. Nature 320(6063):584-8 |
| abstractText | In response to invasive stimuli macrophages secrete cachectin, a multipotent protein. Prominent among its biological effects is the ability to induce wasting (cachexia) as well as a lethal state of shock. The identity of cachectin and tumour necrosis factor has led to a new view of its therapeutic potential. |
