Primary Identifier | MGI:1321159 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 19052 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.3.0) Enables GABA receptor binding activity and protein serine/threonine phosphatase activity. Involved in T cell homeostasis; negative regulation of glycolytic process through fructose-6-phosphate; and regulation of intracellular signal transduction. Acts upstream of or within mesoderm development. Located in chromosome, centromeric region; cytosol; and plasma membrane. Part of protein phosphatase type 2A complex. Is active in synapse. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human PPP2CA (protein phosphatase 2 catalytic subunit alpha). PHENOTYPE: Homozygous null embryos die before gastrulation and exhibit widespread degeneration. Mesoderm is not formed. [provided by MGI curators] |