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Protein Coding Gene : Eif4a3 eukaryotic translation initiation factor 4A3
Primary Identifier  MGI:1923731 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  192170
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable several functions, including ATP binding activity; RNA binding activity; and RNA helicase activity. Acts upstream of or within positive regulation of mRNA splicing, via spliceosome and positive regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in submandibular gland primordium; telencephalon; testis; and vibrissa. Human ortholog(s) of this gene implicated in intellectual disability. Orthologous to human EIF4A3 (eukaryotic translation initiation factor 4A3).
  • synonyms:
  • 2400003O03Rik,
  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 48,
  • Ddx48,
  • RIKEN cDNA 2400003O03 gene,
  • eukaryotic translation initiation factor 4A3,
  • Eif4a3,
  • mKIAA0111
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Features --> Cross References

Genome

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

19 Pathways

Trail: ProteinCodingGene

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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