Primary Identifier | MGI:6358613 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Golga2 |
Transmission | Germline | Strain of Origin | 129 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A loxP site was inserted upstream of exon 14 and an FRT flanked neo cassette and loxP site were inserted downstream of exon 14 via homologous recombination. Recombinase mediated recombination removed exon 14 and the neo cassette. Real-time PCR analysis demonstrated a dramatic reduction of mRNA expression in the testes, lung, liver and kidney of adult homozygous mutant mice. |