Primary Identifier | MGI:5476622 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Stx11 |
Transmission | Germline | Strain of Origin | C57BL/6NTac |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A resistance cassette (FRT site, neo resistance gene, loxP site, FRT site and loxP site) was inserted downstream of exon 3. An additional loxP site was inserted upstream of exon 3. Flp-mediated recombination removed the neo cassette. Cre-mediated recombination removed exon 3. Western blot analysis confirmed the absence of protein expression in CD8+ T cells. |