Primary Identifier | MGI:5447927 | Allele Type | Targeted |
Gene | Vav1 | Transmission | Germline |
Strain of Origin | 129S4/SvJae-Tg(Prm-cre)70Og | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Mutations were inserted in exon 10 which caused Leu334Ala and Lys335Ala amino acid residue changes. In addition,k a floxed neo cassette was inserted in intron 9. Subsequent cre mediated excision removed the neo cassette. |