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Protein Coding Gene : Washc2 WASH complex subunit 2

Primary Identifier  MGI:106463 Organism  mouse, laboratory
Chromosome  6 NCBI Gene Number  28006
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable phosphatidylinositol phosphate binding activity; phosphatidylinositol-3,4-bisphosphate binding activity; and retromer complex binding activity. Predicted to be involved in protein localization to endosome and retrograde transport, endosome to Golgi. Predicted to act upstream of or within protein transport. Part of WASH complex. Is expressed in several structures, including extraembryonic component; liver; and neural retina. Orthologous to several human genes including WASHC2A (WASH complex subunit 2A).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit placentation defects with abnormal trophoblast layer formation and complete lethality throughout fetal growth and development. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA C530005J20 gene,
  • family with sequence similarity 21,
  • Washc2,
  • DNA segment, Chr 6, Wayne State University 116, expressed,
  • Fam21,
  • D6Wsu116e,
  • C530005J20Rik,
  • MGD-MRK-34157,
  • WASH complex subunit 2,
  • MGI:1915404

Features --> Cross References

Genome

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

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Expression

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Disease

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