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Publication : Molecular cloning of a mouse homologue for the Drosophila splicing regulator Tra2.

First Author  Segade F Year  1996
Journal  FEBS Lett Volume  387
Issue  2-3 Pages  152-6
PubMed ID  8674539 Mgi Jnum  J:33424
Mgi Id  MGI:80904 Doi  10.1016/0014-5793(96)00496-6
Citation  Segade F, et al. (1996) Molecular cloning of a mouse homologue for the Drosophila splicing regulator Tra2. FEBS Lett 387(2-3):152-6
abstractText  We report the identification of a mouse cDNA, SIG41, encoding a protein of 288 amino acids that is 45% identical (58% similar) to the Drosophila splicing regulator Tra2. SIG41 cDNA contains four polyadenylation signals whose alternative use gives rise to four types of transcripts (2.1, 2.0, 1.5, and 1.4 kb) in mouse cells. Northern analysis and RT-PCR assays showed that SIG41 mRNA is present in virtually all the cell lines and tissues studied, with remarkable levels of expression in uterus and brain tissues. Differential stability of the SIG41 mRNAs was detected in mouse macrophage cells.
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