Primary Identifier | MGI:7490108 | Allele Type | Targeted |
Attribute String | Conditional ready, Null/knockout | Gene | Tlr3 |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A floxed transcriptional termination element was inserted between exons 3 and 4 of the gene. A lack of TLR3 protein expression was shown in bone marrow-derived macrophages generated from homozygous mice. If cre-mediated recombination occurs, normal expression of the gene is restored. |